Breast Cancer Battle - More Genes Discovered
Researchers have discovered nine new genes which are involved in the development of breast cancer, bringing the number of all genes so far associated with the development of breast cancer to 40, according to a study published in Nature. The researchers analyzed all genes in the genomes of 100 breast cancer cases and discovered that there were different mutated cancer-causing genes in different samples of cancer, suggesting that breast cancer is genetically diverse... (Source: Health News from Medical News Today)
Assessment of the stability of 30 antipsychotic drugs in stored blood specimens
Abstract: The stability of 30 common antipsychotics (APs) in spiked whole blood was investigated over ten weeks in a preliminary experiment (designated “P experiment”). Pools of blank blood spiked with drugs at two different therapeutic levels were stored at four different temperatures: 20°C, 4°C, −20°C, and −60°C and extracted once weekly in duplicate, using a previously published method. A loss of 15% of the initial drug concentration was considered to indicate possible instability and the respective drugs were selected for further investigation in a final experiment (designated “F experiment”).Eight APs (chlorpromazine, chlorprothixene, fluspirilene, droperidol, olanzapine, thioridazine, triflupromazine, and ziprasidone) were incorporated into the F experiment. The same...