Doctors Test Milk Thistle To Counter Amanitin Toxins In The Liver Following 4 Acute Mushroom Poisonings In 2 Weeks
On September 12, 2011, a Springfield, Virginia man arrived at MedStar Georgetown University Hospital (MGUH) in the early stages of liver failure. The man had mistakenly eaten poisonous mushrooms, handpicked from his yard. He would be the first of four patients in the course of two weeks to seek treatment at MGUH for mushroom (amanitin) poisoning... (Source: Health News from Medical News Today)
Angiotensin-converting enzyme inhibition augments the expression of rat elastase-2, an angiotensin ii-forming enzyme.
We examined the expression levels of transcripts for elastase-2, a chymostatin-sensitive serine protease identified as the alternative pathway for angiotensin II (Ang II) generation from angiotensin I (Ang I) in the rat vascular tissue, and the relative role of ACE-dependent and -independent pathways in generating Ang II in the rat isolated carotid artery rings of spontaneously hypertensive rats (SHR) and Wistar normotensive rats (WNR) treated with enalapril for 7 days. Enalapril treatment decreased blood pressure of SHR only and resulted in significantly more elastase-2 mRNA expression in carotid artery of both enalapril-treated WNR and SHR. Captopril induced a comparable rightward shift of concentration-response curves to Ang I in vehicle and enalapril-treated rats, although this effect ...