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Effect of letrozole on the uterine Doppler flow indices during early pregnancy: a randomised trial.
Conclusion: We demonstrated that the use of letrozole in first trimester pregnancy suppressed serum estradiol level, but resulted in an increase in blood flow to the uterus. Further studies should be carried out to elucidate the mechanism of letrozole pretreatment in medical abortion. Copyright © 2012 ISUOG. Published by John Wiley Sons, Ltd. PMID: 22302719 [PubMed - as supplied by publisher] (Source: The Ultrasound Review of Obstetrics and Gynecology)