Farmers' markets are good for you
Susan Hendricks reports farmers' markets are good for you and good for the economy. (Source: CNN.com - Health)
H1‐antihistamines and urticaria: how can we predict the best drug for our patient?
AbstractUrticaria, and especially chronic spontaneous urticaria, is a difficult condition to treat. Consequently, clinicians need to use the best H1‐antihistamines currently available and the pharmaceutical industry need to keep developing H1‐antihistamines that are more effective than the ones we have today. To do this we need to be able to compare the clinical efficacy of both established and new drugs. Obviously, the ideal way to do this is to use head to head studies in CSU. However, such studies are extremely expensive and, in the case of novel molecules, have ethical and logistical problems. Consequently, we need to have predictive models. While determination of Ki, an indicator of the in vitro potency of an H1‐antihistamine, may help in the initial selection of candidate molec...