Twenty-five years in the making: flecainide is safe and effective for the management of atrial fibrillation
The objective of this article is to review the literature pertaining to the pharmacological characteristics, safety and efficacy of flecainide, and to place this drug in the context of current therapeutic management strategies for AF. (Source: Europace)
Case review: Tachycardia due to atrial flutter following treatment of atrial fibrillation with flecainide
Source: BMJ
Area: News
The British Medical Journal has featured an article in which the authors highlight the possible 'unwanted effect' of using flecainide for atrial fibrillation.
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According the article, current guidelines include flecainide as a possible treatment for chemical cardioversion and maintaining sinus rhythm in paroxysmal atrial fibrillation, but an important, under-recognised complication of flecainide is the transformation of rhythm from atrial fibrillation to atrial flutter. The authors present four cases in which this occurred, and conclude that:
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This case series highlights the need to be vigilant of the clinically important proarrhythmic effects associated with flecainide, a drug increasingly used in primary care and emergency departments. Flecaini...