Bavarian Nordic says U.S. backs new Imvamune study
COPENHAGEN (Reuters) - Danish biopharma firm Bavarian Nordic said on Tuesday that the U.S. Department of Health and Human Services has supported the initiation of an expanded phase 3 study of its smallpox vaccine Imvamune. (Source: Reuters: Health)

Interactive effects of metal contamination and pathogenic organisms on the introduced marine bivalve Ruditapes philippinarum in European populations.
Authors: Paul-Pont I, de Montaudouin X, Gonzalez P, Jude F, Raymond N, Paillard C, Baudrimont M In natural environment, marine organisms are concomitantly exposed to pollutants and multiple disease agents resulting in detrimental interactions. The present study evaluated interactive effects of metal contamination (cadmium) and pathogenic organisms (trematode parasites Himasthla elongata and pathogenic bacteria Vibrio tapetis) singularly and in combination on the bivalve Ruditapes philippinarum, an introduced species to Europe, under laboratory controlled conditions. After 7 days, metal bioaccumulation and pathogen load were analyzed as well as metallothionein (MT) response and hemocyte concentrations and activities. Results showed that infection by opportunistic pathogens affects metal...