IVF overhaul proposed
Same-sex couples and women aged up to 42 may soon be eligible for IVF treatment, according to new draft guidelines published today. The proposals were issued by the National Institute for health and Clinical Excellence (NICE) and featured prominently in the news, although they also include a range of recommendations not covered by the media. NICE last issued full guidelines on IVF in 2004, but since then there have been advances in the drugs and techniques available. To take these changes and recent evidence into account, NICE has drawn up new extensive guidelines on everything from who should get IVF to the individual drugs that should be used. The provisional recommendations include raising the upper age limit for IVF from 39 to 42 for some women and offering fertility treatments to sam...

Prescription Acetaminophen Ingestions Associated with Hepatic Injury and Death
Abstractnbsp;nbsp;The U.S. Food and Drug Administration has formally requested that pharmaceutical manufacturers limit the amount of acetaminophen (APAP) in prescription products. The goal of this study was to describe a state-wide poison control system’s experience with prescription APAP ingestions that resulted in hepatic injury or death. Retrospective analysis of statewide California Poison Control System electronic database for cases from the years 2000 through 2009. Inclusion criteria: adults ≥18nbsp;years of age following therapeutic use of an acetaminophen-containing prescription with laboratory evidence of liver injury. Forty cases met the inclusion criteria. All cases involved at least two concurrent acetaminophen-containing products. Prescription APAP strengths of 50...