02 Characterising cardiovascular safety profile of muscarinic antagonist, ipratropium
Chronic Obstructive Pulmonary Disease (COPD) is a disease characterised by inflammation of the airways which accounts for the fourth highest cause of global death. The functional role of Muscarinic receptor antagonists such as Ipratropium Bromide (Atrovent) and Tiotropium Bromide (Spiriva) has been shown to successfully improve pulmonary function in COPD patients. Recent studies have associated an increased risk of cardiovascular events in COPD patients currently receiving treatment with Muscarinic receptor antagonists such as Ipratropium (Ogale et al, 2010). The study aimed to investigate the effects of Ipratropium on the myocardium subjected to ischaemia-reperfusion (I/R). Langendorff hearts were subjected to control or I/R in the absence or presence of Ipratropium (1nbsp;nM, 10nbsp;nM...div id=medwormpbiMedWorm Message:/i/b Please have a look at this new site driven by MedWorm: a href=http://www.thebreastcancerdaily.com/ target=_blankThe Breast Cancer Daily/a/p/div

IPRATROPIUM BROMIDEsolution [Mylan Pharmaceuticals Inc.]
Updated Date: Mar 25, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))