Sublingual isosorbide dinitrate for the detection of obstruction in hypertrophic cardiomyopathy
Conclusion The ISDN test is a reliable screening method for the detection of an HCM obstruction, however, the measurement should be delayed 5ndash;10 min after the application of ISDN. Patients with negative ISDN tests should undergo exercise echocardiography. (Source: European Journal of Echocardiography)

Vascular Dysfunction in Experimental Diabetes Is Improved by Pentaerithrityl Tetranitrate but not Isosorbide-5-Mononitrate Therapy.
CONCLUSIONS In contrast to ISMN, the organic nitrate, PETN, improves endothelial dysfunction in diabetes by preventing eNOS uncoupling and NADPH oxidase activation, thereby reducing oxidative stress. Thus, PETN therapy may be suited to treat patients with cardiovascular complications of diabetes. PMID: 21844097 [PubMed - as supplied by publisher] (Source: Diabetes)