For Pulmonary Hypertension, Inhibition Of PBEF Is A Possible Therapeutic Target
Inhibition of pre-B Cell Colony-Enhancing Factor (PBEF) could be a potential therapeutic target for pulmonary hypertension (PH), according to a preclinical study in an animal model of PH. PBEF expression appears to be significantly increased in PH. Accordingly, we examined whether inhibiting PBEF could prevent and reverse PH in rats, said Roberto Machado, MD, associate professor of medicine at the University of Illinois at Chicago... (Source: Health News from Medical News Today)
Expression of AMPA receptor subunits in hippocampus after status convulsion
Conclusionsnbsp;nbsp;Immature brain was more resistant to seizure-induced neural damage. The time course of reduction and recovery differed for
each subunit and was dependent on developmental stage. The increased expression of GluR2 could confer early but transient
protection in the immature brain after SC.
Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00381-012-1747-3Authors
Yue Hu, Department of Neurology, Children’s Hospital, Chongqing University of Medical Sciences, No.136 Zhongshan 2nd Road, Yu Zhong District, Chongqing, 400014 ChinaLi Jiang, Department of Neurology, Children’s Hospital, Chongqing University of Medical Sciences, No.136 Zhongshan 2nd Road, Yu Zhong District, Chongqing, 400014 ChinaHengsheng Chen, Ministry of Education Key L...div id=medwormpbiMedWorm Message:/i/b Please have a look at this new site driven by MedWorm: a href=http://www.thebreastcancerdaily.com/ target=_blankThe Breast Cancer Daily/a/p/div