I'm an 'older' mum whose son was conceived by IVF - so why am I uneasy about the NHS offering more women like me the same chance of motherhood?
My concerns have less to do with morality and more to do with the reality of conception rates, says Alexandra Grant. (Source: Telegraph Health)

Effect of prostaglandin synthetase inhibitors on renal blood flow in the rat
Using a small-diameter electromagnetic flow transducer, the effect on the autoregulation of renal blood flow (RBF) of two structurally different prostaglandin synthetase inhibitors, indomethacin, 4 mg/kg BW, and meclofenamate, 5 mg/kg BW, was studied in nondiuretic rats anesthetized with either the oxybarbiturate, sodium pentobarbital, or the thiobarbiturate, Inactin. Regardless of the anesthetic agent, RBF remained relatively constant above a perfusion pressure of 105 mmHg. Treatment with either indomethacin or meclofenamate had no measurable effect on the autoregulatory response. Each agent, however, resulted in an increase in the renal vascular response to exogenous angiotensin II, an effect consistent with prostaglandin synthetase inhibition. Base-line RBF was significantly reduced by ...