Efficacy of low-dose hydrochlorothiazide in combination with telmisartan on early morning blood pressure in uncontrolled hypertensive patients.
Authors: Makita S, Abiko A, Naganuma Y, Tamada M, Nakamura M Hypertensive patients whose BP was uncontrolled despite the use of antihypertensive agents, including an ARB (candesartan 8 mg/day or valsartan 80 mg/day), were enrolled. The patients were randomly assigned to combination therapy with telmisartan 40 mg/day (changed from current ARB) and hydrochlorothiazide (HCTZ) 12.5 mg/day (T + H, n = 32) or to no change in their current drug regimen (CTL, n = 32). The observation period was 12 weeks. The office and home BPs were significantly reduced in the T + H compared to those in the CTL. A sufficient and long-acting BP lowering effect, as reflected in decreased early morning BP, was obtained with the combination of low-dose HCTZ and telmisartan without apparent metabolic deterioration...

VSolvit LLC Receives Grand Challenges Explorations Grant For...
VSolvit announced today that it is a Grand Challenges Explorations winner, an initiative funded by the Bill Melinda Gates Foundation. Payal Kamdar, CEO will pursue an innovative global health...(PRWeb May 23, 2012)Read the full story at http://www.prweb.com/releases/2012/5/prweb9535043.htm (Source: PRWeb: Medical Pharmaceuticals)