Biosynthesis: Ringing in a new view
Nature Chemical Biology 8, 505 (2012).
doi:10.1038/nchembio.973
Author: Wendy L Kelly
Heterocycles such as thiazoles are introduced into ribosomally synthesized peptide metabolites by post-translational modification. The enzyme that installs those rings has been identified, providing insight into heterocyclization biochemistry and the potential capabilities of an entire protein family. (Source: Nature Chemical Biology)
Breast Cancer Battle - More Genes Discovered
Researchers have discovered nine new genes which are involved in the development of breast cancer, bringing the number of all genes so far associated with the development of breast cancer to 40, according to a study published in Nature. The researchers analyzed all genes in the genomes of 100 breast cancer cases and discovered that there were different mutated cancer-causing genes in different samples of cancer, suggesting that breast cancer is genetically diverse... (Source: Health News from Medical News Today)