Prostaglandin E2 induces spontaneous rhythmic activity in mouse urinary bladder independently of efferent nerves
Conclusions and Implications:  It is argued that depolarization alone is sufficient to explain a functional increase in intercellular coupling. The action of PGE2 to increase detrusor spontaneous rhythmic activity does not require parasympathetic nerves. (Source: British Journal of Pharmacology)

Wide Variation in PCI for 'Unclear Indications'Wide Variation in PCI for 'Unclear Indications'
The latest study on this subject has found that 17% of hospitals in a large US sample conducted at least one-fifth of their procedures in patients whose indications for the procedure were unclear. Heartwire (Source: Medscape Today Headlines)