Health benefits of POM juice overstated, judge rules
POM Wonderful, perhaps the best-known purveyor of pomegranate juice, has failed to prove that its tangy thirst-quencher can prevent or reduce the risk of heart disease, prostate cancer and erectile dysfunction, a U.S. judge says. (Source: CTV Health)
Pilocarpine-induced status epilepticus alters hippocampal PKC expression in mice.
Authors: Liu JX, Liu Y, Tang FR
We investigated the protein expression of different protein kinase C (PKC) isoforms (PKC-alpha, PKC-beta1, PKC-beta2, PKC-gamma, PKC-delta, PKC-epsilon, PKC-eta and PKC-zeta) in the hippocampus of normal control mice and progressive changes in PKC isoforms expression during and after pilocarpine induced status epilepticus (PISE). We showed the reduced expression of PKC-delta, PKC-eta and PKC-zeta in interneurons in the CA1 area and in the hilus of the dentate gyrus during or after PISE. Increased expression of PKC-alpha and PKC-beta1 was demonstrated in the stratum pyramidale of CA3 area, and PKC-epsilon was up-regulated in the stratum lucidum of the CA3 area during or after PISE. Our results suggest that hippocampal PKC isoforms may play different roles...