Retrieval per se is not sufficient to trigger reconsolidation of human fear memory.
Authors: Sevenster D, Beckers T, Kindt M Abstract Ample evidence suggests that consolidated memories, upon their retrieval, enter a labile state, in which they might be susceptible to change. It has been proposed that memory labilization allows for the integration of relevant information in the established memory trace (i.e., updating). Memory labilization and reconsolidation do not necessarily occur when a memory is being reactivated, but only when there is something to be learned during memory retrieval (i.e., prediction error). Thus, updating of a fear memory trace should not occur under retrieval conditions in which the outcome is fully predictable (i.e., no prediction error). Here, we addressed this issue, using a human differential fear conditioning procedure, by eliminating ...

Mu, Delta, and Kappa opioid receptor agonists induce peripheral antinociception by activation of endogenous noradrenergic system
This study provides evidence that DAMGO, SNC80, or bremazocine induces peripheral antinociception by noradrenaline release and interaction with adrenoceptors. © 2012 Wiley Periodicals, Inc. (Source: Journal of Neuroscience Research)div id=medwormpbiMedWorm Message:/i/b Please support the a href=http://www.doctorsinchains.org/ target=_blankDoctors In Chains/a campaign for the a href=http://www.doctorsinchains.org/medics/a tortured and sentenced for up to 15 years in a href=http://www.doctorsinchains.org/Bahrain/a. a href=https://twitter.com/#!/search/%23FreeDoctors#FreeDoctors/a/p/div