Abatacept Versus Other Biologics in Rheumatoid ArthritisAbatacept Versus Other Biologics in Rheumatoid Arthritis
Are all biologic agents currently used for the treatment of RA similarly effective? Arthritis Research Therapy (Source: Medscape Today Headlines)

A Titrate‐to‐Goal Study of Switching Patients Uncontrolled on Antihypertensive Monotherapy to Fixed‐Dose Combinations of Amlodipine and Olmesartan Medoxomil ± Hydrochlorothiazide
J Clin Hypertens (Greenwich).In the prospective, open‐label, titrate‐to‐goal Blood Pressure Control in All Subgroups With Hypertension (BP‐CRUSH) study, 999 patients with hypertension uncontrolled on monotherapy (mean age, 55.6±11.4 years; baseline blood pressure [BP], 153.7±9.2/91.9±8.6 mm Hg) were switched to fixed‐dose amlodipine/olmesartan medoxomil (AML/OM) 5/20 mg. Patients were uptitrated every 4 weeks to AML/OM 5/40 mg and 10/40 mg to achieve BP lt;120/70 mm Hg. Patients were subsequently uptitrated every 4 weeks to AML/OM+hydrochlorothiazide (HCTZ) 10/40+12.5 mg and 10/40+25 mg to achieve BP lt;125/75 mm Hg. The primary end point, the cumulative percentage of patients achieving seated systolic BP lt;140 mm Hg (lt;130 mm Hg for patients with d...