Determining How Brain Acid Affects Brain Function
A study by Iowa University neuroscientist John Wemmie, M.D., Ph.D. and published in the Proceedings of the National Academy of Sciences (PNAS) Early Edition reveals that elevated acidity or low pH-levels are associated with panic disorders, anxiety and depression and that changes in the brain's acidity are significant for normal brain activity. Wemmie, a UI associate professor of psychiatry says: We are interested in the idea that pH might be changing in the functional brain because we've been hot on the trail of receptors that are activated by low pH... (Source: Health News from Medical News Today)
Statin medication in patients treated with antiepileptic drugs in Norway
ConclusionsThe present study shows that the interaction risk between CYP3A4‐metabolized statins and EIAEDs is largely overlooked in Norwegian clinical practice. To avoid therapeutic failure of statin treatment in patients using AEDs, implementation of strategies for systematic management of drug interactions is warranted. Copyright © 2012 John Wiley Sons, Ltd. (Source: Pharmacoepidemiology and Drug Safety)