Finally, effective migraine relief for teenagers?
Adolescent migraine sufferers soon may be able to get the same relief as adults. Does the combination
of sumatriptan and naproxen sodium stack up against teenage migraine pain and its associated
symptoms? (Source: Modern Medicine Contemporary Pediatrics)
Genetic epidemiology and pharmacogenetics in irritable bowel syndrome
The objectives of this review are twofold. Our first objective is to evaluate the evidence supporting a role for genetics in irritable bowel syndrome (IBS). Specific examples of the associations of genetic variation and symptoms, syndromes, and intermediate phenotypes, including neurotransmitter (serotonergic, alpha;2-adrenergic, and cannabinoid) mechanisms, inflammatory pathways (IL-10, TNFalpha;, GNbeta;3, and susceptibility loci involved in Crohn's disease), and bile acid metabolism, are explored. The second objective is to review pharmacogenetics in IBS, with the focus on cytochrome P-450 metabolism of drugs used in IBS, modulation of motor and sensory responses to serotonergic agents based on the 5-hydroxytryptamine (5-HT) transporter-linked polymorphic region (5-HTTLPR) and 5-HT3 ...div id=medwormpbiMedWorm Message:/i/b Please have a look at this new site driven by MedWorm: a href=http://www.thebreastcancerdaily.com/ target=_blankThe Breast Cancer Daily/a/p/div