Doctor: Teens' mystery illness not a hoax
More at N.Y. school diagnosed with mysterious tics; Neurologist says they suffer conversion disorder - real symptoms without a cause (Source: Health News: CBSNews.com)
A Novel Synergistic Galactomannan-Based Unit Dosage Form for Sustained Release of Acarbose.
Authors: Kumar RV, Sinha VR
Abstract
In the current study, the potential of a novel combination of a galactomannan with acarbose (100 mg) was evaluated for attaining a desired hypoglycaemic effect over a prolonged period of time. Three major antidiabetic galactomannans viz., fenugreek gum, boswellia gum, and locust bean gum were selected in order to achieve a synergistic effect in the treatment alongwith retardation in drug release. In vitro studies indicated that batches containing various proportions of fenugreek gum (AF40-60) were able to control drug release for a longer duration of approximately 10-12 h. In contrast, the matrices prepared using boswellia and locust bean gum were able to sustain the release for relatively shorter durations. Drug release mainly followed first-...