Racial differences in sudden cardiac death among hypertensive patients during antihypertensive therapy: The LIFE study
Conclusions:
Black hypertensive patients are at increased risk of SCD. The higher risk of SCD in black patients persists after adjusting for the higher prevalence of risk factors in black patients, in-treatment blood pressure, and the established predictive value of in-treatment electrocardiographic left ventricular hypertrophy and heart rate for SCD in this population. (Source: Heart Rhythm)div id=medwormpbiMedWorm Message:/i/b Please support the a href=http://www.doctorsinchains.org/ target=_blankDoctors In Chains/a campaign for the a href=http://www.doctorsinchains.org/medics/a tortured and sentenced for up to 15 years in a href=http://www.doctorsinchains.org/Bahrain/a. a href=https://twitter.com/#!/search/%23FreeDoctors#FreeDoctors/a/p/div
Suppression of colitis in mice by cl-amidine: a novel peptidylarginine deiminase (pad) inhibitor.
SUPPRESSION OF COLITIS IN MICE BY CL-AMIDINE: A NOVEL PEPTIDYLARGININE DEIMINASE (PAD) INHIBITOR.
Am J Physiol Gastrointest Liver Physiol. 2011 Mar 17;
Authors: Chumanevich AA, Causey CP, Knuckley BA, Jones JE, Poudyal D, Chumanevich AP, Davis T, Matesic LE, Thompson PR, Hofseth LJ
Inflammatory Bowel Diseases (IBDs), mainly Crohn's Disease (CD) and Ulcerative Colitis (UC) are dynamic, chronic inflammatory conditions that are associated with an increased colon cancer risk. Inflammatory cell apoptosis is a key mechanism for regulating IBD. Protein Arginine Deiminases (PADs) catalyze the post-translational conversion of peptidyl-arginine to peptidyl-citrulline in a calcium-dependent, irreversible reaction, and mediate the effects of pro-inflammatory cytokines. Because PAD levels a...
