Prescription Drug Search Results: Clomipramine

CLOMICALM (Clomipramine Hydrochloride) Tablet CLOMIPRAMINE (Clomipramine Hydrochloride) Powder [Novartis Animal Health US, Inc.]
Updated Date: Jan 20, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Evidence for a differential opioidergic involvement in the analgesic effect of antidepressants: prediction for efficacy in animal models of neuropathic pain?
Conclusions and Implications: The opioid system appears to be involved in the mechanism of action of antidepressants that only have an anti‐hyperalgesic effect (clomipramine iand milnacipran) but not in those (duloxetine) that have a stronger (i.e. antinociceptive) effect. These differences between the antidepressants occurred whatever the aetiology of the neuropathy and, if confirmed in clinical trials, could be used to decide which antidepressant is administered to a patient with neuropathic pain. (Source: British Journal of Pharmacology)