Enobia Provides Update On Progress With ENB-0040, A Bone-Targeted Enzyme Replacement Therapy For Hypophosphatasia
Enobia Pharma provided an update on key developments in its comprehensive effort to develop ENB-0040 (asfotase alfa), an experimental bone-targeted enzyme replacement therapy, for the treatment of hypophosphatasia (HPP). Hypophosphatasia is a rare, inherited, and sometimes fatal metabolic bone disease that affects individuals of all ages. Enobia announced today that it has been issued United States Patent No. 7,763,712 B2, providing robust intellectual property coverage for targeting alkaline phosphatase to bone. Coverage also extends to methods used to treat hypophosphatasia... (Source: Health News from Medical News Today)
Effect of estrogen on tissue elasticity of the ligament proper in rabbit anterior cruciate ligament: measurements using scanning acoustic microscopy
Conclusionnbsp;nbsp;The results of the present study indicated that estrogen altered the tissue elasticity of rabbit ACL. Estrogen may constitute
one of the pathogenetic factors in ACL rupture in female athletes.
Content Type Journal ArticleDOI 10.1007/s00776-010-1474-0Authors
Koshi Hattori, Department of Orthopaedic Surgery, Yamagata Prefectural Shinjo Hospital, Shinjo, JapanHirotaka Sano, Department of Orthopaedic Surgery, Tohoku University School of Medicine, 1-1 Seiryomachi, Aoba-ku, Sendai, 980-8574 JapanTatsuro Komatsuda, Department of Orthopaedic Surgery, North Sendai Orthopaedic Clinic, Sendai, JapanYoshifumi Saijo, Biomedical Imaging Laboratory, Graduate School of Biomedical Engineering, Tohoku University, Sendai, JapanTakehiko Sugita, Department of Orthopaedic Surge...
