Living‐donor liver transplantation for propionic acidemia
This study retrospectively reviewed three children with neonatal‐onset propionic acidemia who received LDLT. Between November 2005 and December 2010, 148 children underwent LDLT, with an overall patient survival of 90.5%, in our center. Three patients were indicated for transplantation because of propionic acidemia. All recipients achieved a resolution of metabolic derangement and better quality of life with protein restriction and medication, although urine methylcitrate and serum propionylcarnitine levels did not decrease markedly. LT can reduce the magnitude of progressive cardiac/neurologic disability as a result of poor metabolic control. Further evaluation is therefore required to determine the long‐term suitability of this treatment modality. (Source: Pediatric Transplantation)
Second‐line Helicobacter pylori Eradication: A Randomized Comparison of 1‐week or 2‐week Bismuth‐containing Quadruple Therapy
Conclusions: Although PBMT7 was not inferior to PBMT14 statistically, PBMT could not demonstrate enough ITT/PP eradication rate. Therefore, it could be better to extend the duration of treatment for 2 weeks for the second‐line treatment of H. pylori in Korea. (Source: Helicobacter)