ORPHENADRINE CITRATEinjection, Solution [Sagent Pharmaceuticals]
Updated Date: Oct 3, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Muscle relaxants for pain management in rheumatoid arthritis
Source: Cochrane Library
Area: Evidence #62; Drug Class Focused Reviews
Background
Pain management is a high priority for patients with rheumatoid arthritis (RA). Muscle relaxants include drugs that reduce muscle spasm (for example benzodiazepines such as diazepam (Valium), alprazolam (Xanax), lorazepam (Ativan) and non-benzodiazepines such as metaxalone (Skelaxin) or a combination of paracetamol and orphenadrine (Muscol)) and drugs that prevent increased muscle tone (baclofen and dantrolene). Despite a paucity of evidence supporting their use, antispasmodic and antispasticity muscle relaxants have gained widespread clinical acceptance as adjuvants in the management of patients with chronic musculoskeletal pain.
#160;
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Objectives The aim of this review was to determin...