Rabies woman turned away from AE
A woman with rabies twice visited an AE unit in Kent before she was diagnosed and admitted to a London hospital, it emerges. (Source: BBC News | Health | UK Edition)
Possible Usefulness of Growth Hormone/Insulin-Like Growth Factor-I Axis in Alzheimer's disease Treatment.
Authors: Sáez JM
Abstract
Alzheimer's disease (AD) has been traditionally conceptualized as a clinicopathological entity, its definite diagnosis requiring the presence of characteristic pathology together with a dementia clinical picture. The fact that certain AD biomarkers show an acceptable sensitivity and specificity to detect AD pathology has shifted the diagnostic paradigm towards a clinicobiological approach. Neuropathological analysis of AD-affected brains reveals extensive atrophy due to neuronal loss, and accumulation of neurofibrillary tangles and neuritic plaques, surrounded by a tract of neuroinflammation and loss of neurons. Recently, emerging evidence supports the concept that AD is also a disorder of metabolic degeneration. Taken together, the neurochemical changes ...