SERTRALINE HYDROCHLORIDEtablet, Film Coated SERTRALINE HYDROCHLORIDEsolution, Concentrate [Greenstone LLC]
Updated Date: Apr 6, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Sensitivity to changes during antidepressant treatment: a comparison of unidimensional subscales of the Inventory of Depressive Symptomatology (IDS-C) and the Hamilton Depression Rating Scale (HAMD) in patients with mild major, minor or subsyndromal depression
Abstractnbsp;nbsp;In the efficacy evaluation of antidepressant treatments, the total score of the Hamilton Depression Rating Scale (HAMD) is
still regarded as the ‘gold standard’. We previously had shown that the Inventory of Depressive Symptomatology (IDS) was more
sensitive to detect depressive symptom changes than the HAMD17 (Helmreich et al. 2011). Furthermore, studies suggest that the unidimensional subscales of the HAMD, which capture the core depressive symptoms,
outperform the full HAMD regarding the detection of antidepressant treatment effects. The aim of the present study was to
compare several unidimensional subscales of the HAMD and the IDS regarding their sensitivity to changes in depression symptoms
in a sample of patients with mild major, minor or subsyndromal de...
