Prospective evaluation of cataract surgery in female patients taking tamsulosin
Intraoperative floppy iris syndrome (IFIS) was first described in 2005 by Chang and Campbell in patients undergoing cataract surgery who were taking tamsulosin.1 Tamsulosin is the most commonly prescribed drug for the treatment of benign prostatic hyperplasia. It acts by selectively antagonising alpha-1a adrenergic receptors (alpha;1ARs) found in the bladder neck and prostate smooth muscle, resulting in relaxation of the muscles and improvement of urinary flow. It has the therapeutic advantage of being uroselective and therefore having fewer cardiovascular side effects.2 The use of tamsulosin has been proposed for various urological conditions in women since it has been proved to have a significant relaxing effect on the urethral tone in healthy women in vivo.3 To the best of our knowledg...
David Cameron's late son Ivan dragged into NHS debate
The Prime Minister's late son was dragged into the debate about NHS reform in a move branded tasteless by Downing Street aides. (Source: Telegraph Health)
