Once-Daily Gabapentin Effective in Postherpetic PainOnce-Daily Gabapentin Effective in Postherpetic Pain
A once-daily formulation of gabapentin G-GR will relieve postherpetic neuralgia within 4 days -- or will not work at all, researchers say. Medscape Medical News (Source: Medscape Medical News Headlines)
Esterase inhibitors as ester-containing drug stabilizers and their hydrolytic products: potential contributors to the matrix effects on bioanalysis by liquid chromatography/tandem mass spectrometry.
CONCLUSIONS: The SRM transitions described here make it possible to directly monitor the inhibitors and their hydrolytic products. In combination with post-column infusion, this methodology provides a powerful tool to routinely monitor the matrix effects-causing inhibitors, so that their matrix effects on the bioanalysis can be evaluated and minimized. Copyright © 2012 John Wiley Sons, Ltd.
PMID: 22555922 [PubMed - in process] (Source: Rapid Communications in Mass Spectrometry : RCM)