Aspirin, steroidal and non-steroidal anti-inflammatory drugs for the treatment of Alzheimer's disease.
CONCLUSIONS: Based on the studies carried out so far, the efficacy of aspirin, steroid and NSAIDs (traditional NSAIDs and COX-2 inhibitors) is not proven. Therefore, these drugs cannot be recommended for the treatment of AD.
PMID: 22336816 [PubMed - in process] (Source: Cochrane Database of Systematic Reviews)
Adult hypophosphatasia with painful periarticular calcification treated with surgical resection
Abstractnbsp;nbsp;Hypophosphatasia is a rare inherited disorder characterized by a low serum alkaline phosphatase (ALP) activity and defective
bone mineralization. Adult hypophosphatasia typically manifests in middle-age as a result of osteomalacia with recurrent stress
fractures of the lower limb. However, considerable variation occurs in the clinical expression of hypophosphatasia, and no
curative treatment has yet been established. We herein report a case of adult hypophosphatasia with painful calcific periarthritis,
which showed improvement after surgical resection. A 32-year-old male was referred to our clinic complaining of pain in his
elbows and knees. A painful subcutaneous mass was palpable on his right lateral epicondyle, where periarticular calcification
was detected by ...
